Catalog# ：AC67564

Clone：OKT3

Isotype：Mouse IgG2a, κ

Endotoxin：Less than 0.001 EU per μg determined by LAL gel clotting assay.

Purity：>99% as determined by SDS-PAGE

            >99% as determined by SEC-HPLC

Antibody Type：Monoclonal

Expressed Host：Stable CHO cell line

Application：T-cell activation

Reactivity：Human

Concentration：1.0 mg/mL

Form：Liquid 

Antibody Type：Monoclonal

Formulation：Supplied as 0.2 μm filtered solution in PBS, pH7.4.

Storage instructions：Shipped at 4°C. Stored at 4°C for 12 months.

Other Names：T3,CD3ε

CD3ε is a 20 kD chain of the CD3/T cell receptor (TCR) complex, which is composed of two CD3ε, one CD3γ, one CD3δ, one CD3ζ (CD247), and a T cell receptor (α/β or γ/δ) heterodimer.

It is a specific marker for T lymphocytes, NK T cells, and some thymocytes. Crosslinking of TCR initiates an intracellular signaling cascade resulting in cellular activation and proliferation.

Please feel free to contact us via support@acnovia.com if you need any further.

1、Biggs MJ, et al. 2011. J. R. Soc. Interface. 8:1462.

2、Manevich-Mendelson E, et al. 2009. Blood 114:2344.

3、Jeong HY, et al. 2008. J. Leuckocyte Biol. 83:755.

4、Li B, et al. 2005. Immunology 116:487.